Section 7.1 Laboratory

Laboratory Report #9

Date

Collection Date: August 12, 2020
Report Date: August 16, 2020

Laboratory

Labcorp

Ordering Physician

Dr. Billy R. Boring, Jr.

Report Type

Targeted Infectious Disease Screening

Laboratory testing included:

QuantiFERON®-TB Gold Plus (Interferon-Gamma Release Assay)

Original Report

PDF: Labcorp – August 12, 2020

One-Page Summary

Purpose of Testing

This laboratory evaluation was performed to determine whether there was evidence of Mycobacterium tuberculosis infection using the QuantiFERON®-TB Gold Plus assay. Unlike the annual comprehensive health evaluations, this was a focused diagnostic study intended to identify either latent or active tuberculosis infection. The report became part of the medical evaluation that occurred shortly before the onset of the systemic inflammatory illness that developed in 2021.

Major Findings

QuantiFERON®-TB Gold Plus

Results

TB1 Antigen Value: 0.01 IU/mL
TB2 Antigen Value: 0.01 IU/mL
Nil Control: 0.01 IU/mL
Mitogen Control: 7.75 IU/mL
Overall Result: Negative

Interpretation

The QuantiFERON®-TB Gold Plus result was negative, indicating no laboratory evidence of tuberculosis infection at the time of testing. The strong mitogen control demonstrated an appropriate immune response, confirming that the test performed as expected and that the negative result was considered valid.

Clinical Significance

This report ruled out tuberculosis as a contributing factor during your medical evaluation.

Because tuberculosis can produce constitutional symptoms such as:

Fatigue
Weight loss
Fever
Elevated inflammatory markers

excluding tuberculosis was an important step in the diagnostic process.

In retrospect, this negative result became valuable because the severe inflammatory illness that emerged several months later required physicians to consider many possible causes before autoimmune and inflammatory disorders became the primary focus.

Overall Interpretation

This focused diagnostic study demonstrated no evidence of latent or active tuberculosis infection. The normal control values confirmed the validity of the assay, making tuberculosis an unlikely explanation for future inflammatory symptoms. Although this report contained only a single laboratory test, it became an important part of the diagnostic workup preceding the systemic inflammatory illness that developed in 2021.

Longitudinal Significance

This report contributes to:

Infectious Disease Evaluation
Medical History Timeline
Systemic Inflammatory Illness Timeline
Differential Diagnosis Archive

Although it contains only one laboratory study, it documents an important diagnostic exclusion during your health journey.

Clinical Importance

⭐⭐ Important Diagnostic Evaluation

This report is significant because it ruled out tuberculosis during the investigation of future inflammatory illness, allowing physicians to focus on other infectious, autoimmune, and inflammatory causes.

Key Findings

QuantiFERON®-TB Gold Plus: Negative
No laboratory evidence of tuberculosis infection.
Appropriate immune response demonstrated by the positive mitogen control.
Tuberculosis effectively excluded as a cause of future inflammatory symptoms.

Related Reports

2020 Comprehensive Laboratory Evaluation
Systemic Inflammatory Illness Timeline
Autoimmune Evaluation
Infectious Disease Studies
Medical History Timeline

Navigation

Previous Report: August 5, 2020 – Comprehensive Annual Health Evaluation
Next Report: February 4, 2021 – Early Systemic Inflammatory Illness Laboratory Evaluation
Return to Laboratory Library
Return to Health Inventory

Observation

This is the first focused diagnostic laboratory study in your Laboratory Library. Unlike the annual health evaluations that monitored overall health, this report addressed a specific clinical question: “Could tuberculosis explain the patient’s symptoms?” The answer was no. As your Health Inventory progresses into the 2021 inflammatory illness, this report becomes an important piece of the diagnostic puzzle because it documents that one major infectious cause had already been investigated and excluded.